Homelessness is a complex public health and social justice issue that extends far beyond the lack of shelter and profoundly affects individuals’ physical health, mental wellbeing, safety, and social participation. This chapter examines homelessness within the framework of community health principles and occupational justice, emphasizing that participation in meaningful daily activities      -including self-care, education, work, and leisure- is a fundamental human right. The chapter outlines definitions and classifications of homelessness, explores its national and international context, and details its wideranging impacts on health. Drawing on global and local best-practice models, including Housing First, street medicine, and services developed by municipalities and civil society in Türkiye, the chapter highlights how sustainable, rights-based, and interdisciplinary approaches are essential in addressing homelessness. From an occupational therapy perspective, homelessness creates profound occupational deprivation, imbalance, alienation, and marginalization. Occupational therapists play a key role in restoring participation by supporting basic needs, strengthening daily living skills, enhancing mental well-being, promoting community belonging, and advocating for accessible environments and housing. The chapter offers multilevel (individual, community, national) intervention strategies grounded in occupational therapy principles, and concludes with sustainable policy recommendations aimed at improving quality of life, fostering social inclusion, and advancing occupational justice for individuals experiencing homelessness.